Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p259 | (1) | WCRB2014

SSP411 a sperm factor involved in oocyte cleavage

Liu Miao , Gu Yihua , Wang Jian , Lu Yi , Yuan Yao , Wu Bin , Chen Ching-Ling C , Shi Huijuan

Introduction: Encoding an 88 kDa protein with a thioredoxin-like domain at the N-terminal region, ssp411 is predominantly expressed at several specific stages from round spermatids to spermatozoa in the rat testis at both mRNA and protein levels. SSP411 is conserved in many species, and can be localized in the testis and mature sperm of human, mouse, and rat.Materials and methods: A line of ssp411 knockout mice (ssp411&#87...